The gene CUL4B, or curlin 4B, codes for proteins. Mental retardation, X-linked, syndromic, Cabezas type, and seizure disorder are among the illnesses linked to CUL4B. Mesodermal Commitment Pathway and Transcription-Coupled Nucleotide Excision Repair (TC-NER) are two of its associated pathways. This gene is associated with the Gene Ontology (GO) annotations for damaged DNA binding and ubiquitin protein ligase binding. CUL4A is a significant paralog of this gene.

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