Hydrocodone and Oxycodone are both known as pain relief medications or opioid medications in the United States, they have so many similarities in their functions and working style on the patient's body but they have some differences also. Here we discuss the major difference between Oxycodone and Hydrocodone which may help you to choose the right medicine for pain relief.

Hydrocodone and Oxycodone: Difference

Hydrocodone and oxycodone are two opioid medicines and they are different from each other. Here we discuss the key difference between these two medicines. 

Mechanism Of Action:

Both Hydrocodone and Oxycodone have similar mechanisms for binding the opioid receptor in the central nervous system and blocking pain signals, both Hydrocodone and Oxycodone work in the brain reward system and change the pain receiver system.

Drug class:

Oxycodone and Hydrocodone both are in the same class called opioid analgesics, in this class medication affects the brain and central nervous system for processing the pain signal, and both are in schedule 2 drugs classes.

 Effectiveness : 

Many people say Oxycodone is a better pain reliever than Hydrocodone but research says that both medicines have equal power to reduce the ongoing pain in the body so Both have the effectiveness to reduce the ongoing pain of the patient. 


There is a small difference between the cost of Hydrocodone and Oxycodone, both have some variants and according to the variants of hydrocodone the price starts from 530$-1500$ (90 tablets), and Oxycodone price starts from 562$-1535$(90tablets), the cost varies each site.


According to the condition of the patient-doctor prescribed the doges, the forms of Oxycodone and Hydrocodone include immediate-release forms taken every 4-6 hours, and extended forms taken every 12 hours for treatment.

Age Restriction:

            Both Oxycodone and Hydrocodone have age reactions, the lower age limit to use 

            Oxycodone is 11 years, and the lower age limit to use Hydrocodone is 18 years, 

            some variants are for adults only, so keep aware of children.

Side effects:

Both medicines have the potential for side effects. Side effects occur when we misuse any medicine or do not take medicine as prescribed. Here look at some possible side effects of these medicines

Common side effects of Oxycodone are Nausea, vomiting, constipation, lightheadedness, dizziness, etc. Common side effects of Hydrocodone are Headache, chills, anxiety, insomnia, drowsiness, etc

Variants of Hydrocodone and Oxycodone:-

Oxycodone and Hydrocodone have many variants for different stages of people, it is mainly for adults not for children, so keep aware of it from children. Some variants of oxycodone are - Oxycodone 30mg, 80mg, 15mg, 10mg, 40mg, 5mg, 20mg, and 60mg. Some variants of hydrocodone are - Hydrocodone 10-325mg, 10-650mg, 10-660mg, m367,5-325mg, 10-500mg, m365


Before taking any medicines consult with your doctor and health care professional about all the possible information related to 

Oxycodone and Hydrocodone which is best : 

According to the studies and some research both have some merits and demerits, both have the power to cure short-term pain in our body but in some cases, Hydrocodone gets better experience in the basic of side effects.so according to the doctor's concern, you should prefer Oxycodone or Hydrocodone as your need.

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