Meridia, or sibutramine, was once prescribed to aid weight loss in individuals who were obese or overweight and had other risk factors such as high blood pressure, diabetes, or high cholesterol. It was typically recommended as part of a comprehensive weight loss program that included diet and exercise.

The medication was generally taken orally as a tablet, usually once daily. It worked by increasing the levels of certain neurotransmitters in the brain, which helped to decrease appetite and promote a feeling of fullness. This, in turn, could lead to reduced food intake and weight loss over time.