Take Tadalista Professional about 30 minutes before sexual activity. Although it can start working in as little as 15 minutes, waiting 30 minutes ensures optimal absorption and effectiveness. For best results, avoid heavy or high-fat meals and excessive alcohol before taking the medication. Heavy meals can delay the onset of effects, and alcohol can reduce the medication’s effectiveness and increase side effects. Complement the medication with a healthy lifestyle, including regular exercise, a balanced diet, and stress management. These factors can significantly impact your overall sexual health and performance.